Contents Volume II Issue I ( 2017)

 
The Importance of Selection of Neuromodulation Therapy in Neurodegenerative Disorders
Abstract:  Neuromodulation therapies generally deal with the provision of pain management, treatment of movement disorders, seizure control by the utilization of brain-controlled devices to individuals with compromised movement. Recent advancement in optogenetics has led to the development of techniques to explore the neural circuitry & biomarkers to track the progression of disease in neurodegenerative ...Read More - Download PDF - View Fulltext
Author/s: 1-Mubashar Rehman
Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.(Corresponding Author)

2-Syeda Komal Fatima
Undergrad Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.

3-Nida Rashid
Undergrad Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.

4-Sana Ali Zahra
Undergrad Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.

Keywords:Neuromodulation therapies, Deep brain stimulation (DBS), Trigeminal Nerve Stimulation (TNS), Peripheral Nerve Stimulation (PNS), Spinal Cord Stimulation (SCS), Transcranial Magnetic Stimulation (TMS)
DOI Number:10.31703/giidr.2017(II-I).01 DOI Link:http://dx.doi.org/10.31703/giidr.2017(II-I).01
Page Nos:1-8 Volume & Issue:II-I
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Declined Drug Susceptibility Mechanisms against Mycobacterium Tuberculosis
Abstract:  Anti-microbial treatment is extensively used in conventional tuberculosis treatment, leading to resistance development. In this review, we summarized the mode of action and susceptibility protocols of anti-Tubercular drugs. An effort to elucidate the role of genetic variations, cell membrane adaptions, and efflux pump modalities in treatment failure will be an asset in devising prospective str ...Read More - Download PDF - View Fulltext
Author/s: 1-Shabana Gulzar Toor
Undergraduate Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

2-Mohammad Faizan Asif
Undergraduate Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

3-Hafsa Abbas
Undergraduate Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, Pakistan.

4-Gul Shehnaz
Chairperson, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.

Keywords:Tuberculosis, Drug resistance, Mechanism of Action, Mutations
DOI Number:10.31703/giidr.2017(II-I).02 DOI Link:http://dx.doi.org/10.31703/giidr.2017(II-I).02
Page Nos:9-27 Volume & Issue:II-I
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Advancements in the Diagnostic and Treatment Approaches of Hepatitis C Virus
Abstract:  HCV virus has been a worldwide health-issue with noted expectancy ranging from 0.6% to 10% depending on geographical factors, and an estimated 71 million individuals worldwide are infected with this chronic virus. Diagnostic methods comprise HCV RNA test, Geno sensor, and laboratory testing, etc. With time there has been an immense number of advancements in HCV treatment. It started with the u ...Read More - Download PDF - View Fulltext
Author/s: 1-Sameena Zehussain
Undergraduate Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan

2-Muhammad Ilyas
Undergraduate Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.

3-Ayesha Ahmad
Undergraduate Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.

4-Mubashar Rehman
Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.(Corresponding Author)

Keywords:Hepatitis C Virus, Genotype, Electrochemical Immunosensors, Geno Sensor, Vaccination, Nontechnology
DOI Number:10.31703/giidr.2017(II-I).03 DOI Link:http://dx.doi.org/10.31703/giidr.2017(II-I).03
Page Nos:28-40 Volume & Issue:II-I
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An Insight of Mechanism of Action of Four Anti-Cancer Drugs
Abstract:  Cancer being a multifarious disease, can be mutated in many ways so that it can enhance the process of proliferation, invasion through an overactive cellular cycle and cell division and by antibacterial and chemotherapeutic drugs is highly guaranteed. The cells can prevent the development of apoptosis by the absence of (TP53) protein i-e tumor suppressor gene, in the necrosis, inflammatory sign ...Read More - Download PDF - View Fulltext
Author/s: 1-Gul Shehnaz
Chairperson, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.(Corresponding Author)

2-Sana Ali Zahra
Undergrad Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.

3-Syeda Komal Fatima
Undergrad Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.

Keywords:Cancer, Chemotherapeutic Drugs, Apoptosis, Tumor Suppressor Gene, Invasion, Metastasis
DOI Number:10.31703/giidr.2017(II-I).04 DOI Link:http://dx.doi.org/10.31703/giidr.2017(II-I).04
Page Nos:41-48 Volume & Issue:II-I
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A Review on the Management of Chronic Hepatitis B and C Infection
Abstract:  Viral hepatitis B and Viral hepatitis C are one of the leading causes of disease and death in the present-day world. These viruses greatly affect the liver by causing inflammation, cirrhosis, fibrosis, hepatocellular carcinoma (HCC) and even causes the death of affected individuals. It requires highly cautious treatment to resolve complications associated with it, including abnormal levels of ...Read More - Download PDF - View Fulltext
Author/s: 1-Marriam Zahid
Undergrad Student, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.

2-Ayesha Hamid
Undergrad Student, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.

3-Aleenah Asad
Undergrad Student, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.

4-Mubashar Rehman
Assistant Professor, Department of Pharmacy, Quaid I Azam University, Islamabad, Pakistan.

Keywords:Hepatitis, Disease, Hepatitis B, Hepatitis C, Infection, Infection Control, Treatment
DOI Number:10.31703/giidr.2017(II-I).05 DOI Link:http://dx.doi.org/10.31703/giidr.2017(II-I).05
Page Nos:59-62 Volume & Issue:II-I
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