01 Pages : 1-7
http://dx.doi.org/10.31703/giidr.2018(III-I).01 10.31703/giidr.2018(III-I).01 Published : Dec 2018A Study on Different Conventional Techniques to Withdraw Blood from Experimental Animals
Blood collection from experimental animals is a common yet crucial procedure that requires immense care and professional experience to ensure propriety and successful trials in the experimental procedure. This article overviews different methods for blood collection, terminal and non-terminal, in different experimental animals, mainly rat, guinea pig, and rabbit. Different sites for the collection of blood have been discussed, along with the pros and cons of administering via these sites. Lastly, it is discussed that the site of selection depends on the sample volume required and the purpose of the experimental procedure; these factors are also discussed in detail in this review article.
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Blood Collection, Anti-Coagulants, Blood Samples, Rats, Rabbit, Guinea Pigs, Mice
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(1) Nida Rashid
Undergraduate Student, Department of Pharmacy, Quaid-I-Azam University, Islamabad, Pakistan.
(2) Ayesha Ahmed
Undergraduate Student, Department of Pharmacy, Quaid-I-Azam University, Islamabad, Pakistan.
(3) Hafsa Shahid
Undergraduate Student, Department of Pharmacy, Quaid-I-Azam University, Islamabad, Pakistan.
(4) Syeda Komal Fatima
Undergraduate Student, Department of Pharmacy, Quaid-I-Azam University, Islamabad, Pakistan.
(5) Mubashir Rehman
Assistant Professor, Department of Pharmacy, Faculty of Biological Sciences, Quaid-I-Azam University, Islamabad, Pakistan.
- Bardelmeijer, H., Buckle, T., Ouwehand, M., Beijnen, J., Schellens, J., & Van Tellingen, O. J. L. a. (2003). Cannulation of the jugular vein in mice: a method for serial withdrawal of blood samples. 37(3), 181-187.
- Birck, M. M., Tveden-Nyborg, P., Lindblad, M. M., & Lykkesfeldt, J. J. J. (2014). Non-terminal blood sampling techniques in guinea pigs. (92), e51982.
- Courtice, F. J. T. J. o. p. (1943). The blood volume of normal animals. 102(3), 290.
- Cuper, N. J., Verdaasdonk, R. M., De Roode, R., De Vooght, K. M., Viergever, M. A., Kalkman, C. J., & De Graaff, J. C. J. C. p. (2011). Visualizing veins with near-infrared light to facilitate blood withdrawal in children. 50(6), 508-512.
- Dang, V., Bao, S., Ault, A., Murray, C., McFarlane- Mills, J., Chiedi, C., . . . Rao, S. J. J. o. t. A. A. f. L. A. S. (2008). Efficacy and safety of five injectable anesthetic regimens for chronic blood collection from the anterior vena cava of guinea pigs. 47(6), 56-60.
- Kalisch, R., Elbel, G.-K., Gössl, C., Czisch, M., & Auer, D. P. J. N. (2001). Blood pressure changes induced by arterial blood withdrawal influence bold signal in anesthesized rats at 7 Tesla: implications for pharmacologic MRI. 14(4), 891- 898.
- Kowarski, C., Giancatarino, C., Kreamer, R., Brecht, D., & Kowarski, A. J. J. o. p. s. (1976). Measurement of sulfamethizole clearance rate by nonthrombogenic constant blood- withdrawal system. 65(3), 450-452.
- Matta, B. F., & Lam, A. M. J. T. J. o. t. A. S. o. A. (1997). The rate of blood withdrawal affects the accuracy of jugular venous bulb: oxygen saturation measurements. 86(4), 806-808.
- Parasuraman, S., Raveendran, R., Kesavan, R. J. J. o. p., & pharmacotherapeutics. (2010). Blood sample collection in small laboratory animals. 1(2), 87.
- Solomon, R. A., Antunes, J. L., Chen, R., Bland, L., & Chien, S. J. S. (1985). Decrease in cerebral blood flow in rats after experimental subarachnoid Hemorrhage: a new animal model. 16(1), 58-64.
- Sorg, D. A., Buckner, B. J. P. o. t. S. f. E. B., & Medicine. (1964). A simple method of obtaining venous blood from small laboratory animals. 115(4), 1131-1132.
- Ungerstedt, U. J. J. o. i. m. (1991). Microdialysis- principles and applications for studies in animals and man. 230(4), 365-373.
- Williams, W. R., & Kendall, L. V. J. L. a. (2015). Blood collection in the guinea pig (Cavia porcellus). 44(6), 207-208.
Cite this article
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APA : Rashid, N., Ahmed, A., & Shahid, H. (2018). A Study on Different Conventional Techniques to Withdraw Blood from Experimental Animals. Global Immunological & Infectious Diseases Review, III(I), 1-7. https://doi.org/10.31703/giidr.2018(III-I).01
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CHICAGO : Rashid, Nida, Ayesha Ahmed, and Hafsa Shahid. 2018. "A Study on Different Conventional Techniques to Withdraw Blood from Experimental Animals." Global Immunological & Infectious Diseases Review, III (I): 1-7 doi: 10.31703/giidr.2018(III-I).01
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HARVARD : RASHID, N., AHMED, A. & SHAHID, H. 2018. A Study on Different Conventional Techniques to Withdraw Blood from Experimental Animals. Global Immunological & Infectious Diseases Review, III, 1-7.
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MHRA : Rashid, Nida, Ayesha Ahmed, and Hafsa Shahid. 2018. "A Study on Different Conventional Techniques to Withdraw Blood from Experimental Animals." Global Immunological & Infectious Diseases Review, III: 1-7
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MLA : Rashid, Nida, Ayesha Ahmed, and Hafsa Shahid. "A Study on Different Conventional Techniques to Withdraw Blood from Experimental Animals." Global Immunological & Infectious Diseases Review, III.I (2018): 1-7 Print.
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OXFORD : Rashid, Nida, Ahmed, Ayesha, and Shahid, Hafsa (2018), "A Study on Different Conventional Techniques to Withdraw Blood from Experimental Animals", Global Immunological & Infectious Diseases Review, III (I), 1-7
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TURABIAN : Rashid, Nida, Ayesha Ahmed, and Hafsa Shahid. "A Study on Different Conventional Techniques to Withdraw Blood from Experimental Animals." Global Immunological & Infectious Diseases Review III, no. I (2018): 1-7. https://doi.org/10.31703/giidr.2018(III-I).01