The emerging pandemic situation has created unease and dismay at every level, from governing bodies to population and from pharmaceutical manufacturers to front-line servers. Everyone is scarified by the death-dealing and ruinous effects of COVID-19. The encouraging and positive news about vaccine development and successful trials of vaccine proved to be remedial, but another dilemma arises in the form of mutation of the deadly virus. Question marks are arising about the lethality of mutated strain, lack of management and protective measures by the governing bodies, and ambiguities are aroused about the effectiveness of vaccines against them. After an all-inclusive and particularized study and genomic examination of the virus, the researchers have put forward the details that Coronavirus Mutation is Worrying but Not Terrifying. The upshot is that it is required to screen, but at present, their mark suggests that the new strain in the UK is more transmissible but neither severe nor resistant.