EFFECT OF COENZYME Q10A AND CLOMIPHENE CITRATE FOR OVULATION INDUCTION IN PATIENTS WITH PCOS AS COMPARED TO CLOMIPHENE CITRATE ALONE

http://dx.doi.org/10.31703/giidr.2023(VIII-I).05      10.31703/giidr.2023(VIII-I).05      Published : Dec 1
Authored by : Iqra Nadeem , Sara Malik , Humaira Nasir , Sadia Ikram , Sana Hassan

05 Pages : 33-39

References

  • Badr, S. A., & Althanoon, Z. A. (2021). A review of the effect of Coenzyme Q10 in patients with polycystic ovary syndrome. Irq J Pharm. 18(1), 108-17. https://www.iasj.net/iasj/download/b5d41671a10d02ff
  • Benton, Y., Hannam, T., Jurisicova, A., Esfandiari, N., & Robert, F., (2014). Coenzyme Q10 supplementation and oocyte aneuploidy in women undergoing IVF –ICSI treatment. Clin Med Insights Reprod Health, 8, 31–6. https://doi.org/10.4137/CMRH.S14681
  • Celik, O., Aydin, S., Celik, N., Ugur, K., Yavuzkir, S., Hatirnaz, S., et al. (2019). Molecular role of peptides/proteins in subfertility of polycystic ovarian syndrome. Mol Cell Biol. 65(3), 32-40. https://doi.org/10.14715/cmb/2019.65.3.5
  • Cirilli, I., Damiani, E., Dludla, P. V., Hargreaves, I., Marcheggiani, F., & Millichap, L. E. et al. (2021). Role of coenzyme Q10 in health and disease: An update on the last 10 years (2010–2020). Antioxidants. 10(8), 1325. https://doi.org/10.3390/antiox10081325
  • Deswal, R., Narwal, V., Dang, A., & Pundir, C. S. (2020). The prevalence of polycystic ovary syndrome: a brief systematic review. J Hum Reprod Sci, 13(4), 261. https://doi.org/10.4103/jhrs.JHRS_95_18
  • El Rafaey, A., Selem, A., & Badawy, A. (2014). Combined coenzyme Q10 and clomiphene citrate for ovulation induction in clomiphene citrate resistant polycystic ovary syndrome. Reprod Biomed Online 29, 119–24. https://doi.org/10.1016/j.rbmo.2014.03.011
  • Ibrahim, S. (2020). Comparative study between L- carnitine versus co-enzyme Q10 as an adjuvant therapy to clomiphene resistant PCOS women on improving pregnancy rate and prevention of early pregnancy loss. Evid Based Women's Health J. 10(2), 133-43. https://doi.org/10.21608/ebwhj.2020.22384.1072
  • Izhar, R., Husain, S., Tahir, M. A., & Husain, S. (2022). Effect of Administrating Coenzyme Q10 with Clomiphene Citrate on Ovulation Induction in Polycystic Ovary Syndrome Cases with Resistance to Clomiphene Citrate: A Randomized Controlled Trial. J Reprod Infertil. 23(3), 36415489. https://doi.org/10.18502/jri.v23i3.10008
  • Joham, A. E., Norman, R. J., Stener-Victorin, E., Legro, R. S., Franks, S., Moran, L. J., Boyle, J., & Teede, H. J. (2022). Polycystic ovary syndrome. Lancet Diabetes Endocrinol. https://doi.org/10.1016/S2213-8587(22)00163-2
  • Karamali, M., & Gholizadeh, M. (2022). The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome. Gynaecol. Endocrinol, 38(1), 45-9. https://doi.org/10.1080/09513590.2021.1991910
  • Lakshmi, B., Bhavani, K., Sudhakar, M., & Parveen, H. (2018). A study on quality of life and effect of coenzyme-Q10 in polycystic ovarian syndrome patients. Int J Adv Pharm Med Bioallied Sci. 6(1), 14-21. https://biomedjournal.com/a-study-on-quality-of-life-and-effect-of-coenzyme-q10-in-polycystic-ovarian-syndrome-patients/
  • Martelli, A., Testai, L., Colletti, A., & Cicero, A. F. (2020). Coenzyme Q10: Clinical applications in cardiovascular diseases. Antioxidants. 9(4), 341. https://doi.org/10.3390/antiox9040341
  • Peker, N., Turan, G., Ege, S., Bademkıran, M. H., Karacor, T., & Erel, Ö. (2021). The effect of clomiphene citrate on oxidative stress parameters in polycystic ovarian syndrome. J Obstet Gynecol. 41(1), 112-7. https://doi.org/10.1080/01443615.2020.1719052
  • Sharideh, H., Zhandi, M., Zeinoaldini, S., Zaghari, M., Sadeghi, M., & Akhlaghi, A., et al. (2020). Beneficial effects of dietary coenzyme Q10 on the productive and reproductive variables of broiler breeder hens. Anim. Reprod. Sci. 213, 106-256. https://doi.org/10.1016/j.anireprosci.2019.106256
  • Sifuentes-Franco, S., & Sánchez-Macías, D. C, (2022). Carrillo-Ibarra S, Rivera-Valdés JJ, Zuñiga LY, Sánchez-López VA. Antioxidant and anti-inflammatory effects of coenzyme Q10 supplementation on infectious diseases. Healthcare 10(3), 487. https://doi.org/10.3390/healthcare10030487
  • Testai, L., Martelli, A., Flori, L., Cicero, A. F., & Colletti, A. (2021). Coenzyme Q10: clinical applications beyond cardiovascular diseases. Nutrients. 13(5), 1697. https://doi.org/10.3390/nu13051697
  • Turri, A., Giannobilo, S. R., Bruge, F., Principi, F., Battistoni, S., & Santoni, F. et al. (2012). Coenzyme Q10 content in follicular fluid and its relationship with oocyte fertilization and embryo grading. Arch Gynecol Obstet, 285, 1173-6. https://doi.org/10.1007/s00404-011-2169-2
  • Wang, L., Tang, J., Wang, L., Tan, F., Song, H., & Zhou, J. et al. (2021). Oxidative stress in oocyte aging and female reproduction. J Cell Physiol, 236(12), 7966-83. https://doi.org/10.1002/jcp.30468
  • Zhang, J., Bao, Y., Zhou, X., & Zheng, L. (2019). Polycystic ovary syndrome and mitochondrial dysfunction. Reproductive Biology and Endocrinology. 17(1), 1-5. https://doi.org/10.1186/s12958-019-0509-4

References

  • Badr, S. A., & Althanoon, Z. A. (2021). A review of the effect of Coenzyme Q10 in patients with polycystic ovary syndrome. Irq J Pharm. 18(1), 108-17. https://www.iasj.net/iasj/download/b5d41671a10d02ff
  • Benton, Y., Hannam, T., Jurisicova, A., Esfandiari, N., & Robert, F., (2014). Coenzyme Q10 supplementation and oocyte aneuploidy in women undergoing IVF –ICSI treatment. Clin Med Insights Reprod Health, 8, 31–6. https://doi.org/10.4137/CMRH.S14681
  • Celik, O., Aydin, S., Celik, N., Ugur, K., Yavuzkir, S., Hatirnaz, S., et al. (2019). Molecular role of peptides/proteins in subfertility of polycystic ovarian syndrome. Mol Cell Biol. 65(3), 32-40. https://doi.org/10.14715/cmb/2019.65.3.5
  • Cirilli, I., Damiani, E., Dludla, P. V., Hargreaves, I., Marcheggiani, F., & Millichap, L. E. et al. (2021). Role of coenzyme Q10 in health and disease: An update on the last 10 years (2010–2020). Antioxidants. 10(8), 1325. https://doi.org/10.3390/antiox10081325
  • Deswal, R., Narwal, V., Dang, A., & Pundir, C. S. (2020). The prevalence of polycystic ovary syndrome: a brief systematic review. J Hum Reprod Sci, 13(4), 261. https://doi.org/10.4103/jhrs.JHRS_95_18
  • El Rafaey, A., Selem, A., & Badawy, A. (2014). Combined coenzyme Q10 and clomiphene citrate for ovulation induction in clomiphene citrate resistant polycystic ovary syndrome. Reprod Biomed Online 29, 119–24. https://doi.org/10.1016/j.rbmo.2014.03.011
  • Ibrahim, S. (2020). Comparative study between L- carnitine versus co-enzyme Q10 as an adjuvant therapy to clomiphene resistant PCOS women on improving pregnancy rate and prevention of early pregnancy loss. Evid Based Women's Health J. 10(2), 133-43. https://doi.org/10.21608/ebwhj.2020.22384.1072
  • Izhar, R., Husain, S., Tahir, M. A., & Husain, S. (2022). Effect of Administrating Coenzyme Q10 with Clomiphene Citrate on Ovulation Induction in Polycystic Ovary Syndrome Cases with Resistance to Clomiphene Citrate: A Randomized Controlled Trial. J Reprod Infertil. 23(3), 36415489. https://doi.org/10.18502/jri.v23i3.10008
  • Joham, A. E., Norman, R. J., Stener-Victorin, E., Legro, R. S., Franks, S., Moran, L. J., Boyle, J., & Teede, H. J. (2022). Polycystic ovary syndrome. Lancet Diabetes Endocrinol. https://doi.org/10.1016/S2213-8587(22)00163-2
  • Karamali, M., & Gholizadeh, M. (2022). The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome. Gynaecol. Endocrinol, 38(1), 45-9. https://doi.org/10.1080/09513590.2021.1991910
  • Lakshmi, B., Bhavani, K., Sudhakar, M., & Parveen, H. (2018). A study on quality of life and effect of coenzyme-Q10 in polycystic ovarian syndrome patients. Int J Adv Pharm Med Bioallied Sci. 6(1), 14-21. https://biomedjournal.com/a-study-on-quality-of-life-and-effect-of-coenzyme-q10-in-polycystic-ovarian-syndrome-patients/
  • Martelli, A., Testai, L., Colletti, A., & Cicero, A. F. (2020). Coenzyme Q10: Clinical applications in cardiovascular diseases. Antioxidants. 9(4), 341. https://doi.org/10.3390/antiox9040341
  • Peker, N., Turan, G., Ege, S., Bademkıran, M. H., Karacor, T., & Erel, Ö. (2021). The effect of clomiphene citrate on oxidative stress parameters in polycystic ovarian syndrome. J Obstet Gynecol. 41(1), 112-7. https://doi.org/10.1080/01443615.2020.1719052
  • Sharideh, H., Zhandi, M., Zeinoaldini, S., Zaghari, M., Sadeghi, M., & Akhlaghi, A., et al. (2020). Beneficial effects of dietary coenzyme Q10 on the productive and reproductive variables of broiler breeder hens. Anim. Reprod. Sci. 213, 106-256. https://doi.org/10.1016/j.anireprosci.2019.106256
  • Sifuentes-Franco, S., & Sánchez-Macías, D. C, (2022). Carrillo-Ibarra S, Rivera-Valdés JJ, Zuñiga LY, Sánchez-López VA. Antioxidant and anti-inflammatory effects of coenzyme Q10 supplementation on infectious diseases. Healthcare 10(3), 487. https://doi.org/10.3390/healthcare10030487
  • Testai, L., Martelli, A., Flori, L., Cicero, A. F., & Colletti, A. (2021). Coenzyme Q10: clinical applications beyond cardiovascular diseases. Nutrients. 13(5), 1697. https://doi.org/10.3390/nu13051697
  • Turri, A., Giannobilo, S. R., Bruge, F., Principi, F., Battistoni, S., & Santoni, F. et al. (2012). Coenzyme Q10 content in follicular fluid and its relationship with oocyte fertilization and embryo grading. Arch Gynecol Obstet, 285, 1173-6. https://doi.org/10.1007/s00404-011-2169-2
  • Wang, L., Tang, J., Wang, L., Tan, F., Song, H., & Zhou, J. et al. (2021). Oxidative stress in oocyte aging and female reproduction. J Cell Physiol, 236(12), 7966-83. https://doi.org/10.1002/jcp.30468
  • Zhang, J., Bao, Y., Zhou, X., & Zheng, L. (2019). Polycystic ovary syndrome and mitochondrial dysfunction. Reproductive Biology and Endocrinology. 17(1), 1-5. https://doi.org/10.1186/s12958-019-0509-4

Cite this article

APA

    APA : Nadeem, I., Malik, S., & Nasir, H. (2023). Effect of Coenzyme Q10a and Clomiphene Citrate for Ovulation Induction in Patients with PCOS as Compared to Clomiphene Citrate alone. Global Immunological & Infectious Diseases Review, VIII(I), 33-39. https://doi.org/10.31703/giidr.2023(VIII-I).05

CHICAGO

    CHICAGO : Nadeem, Iqra, Sara Malik, and Humaira Nasir. 2023. "Effect of Coenzyme Q10a and Clomiphene Citrate for Ovulation Induction in Patients with PCOS as Compared to Clomiphene Citrate alone." Global Immunological & Infectious Diseases Review, VIII (I): 33-39 doi: 10.31703/giidr.2023(VIII-I).05

HARVARD

    HARVARD : NADEEM, I., MALIK, S. & NASIR, H. 2023. Effect of Coenzyme Q10a and Clomiphene Citrate for Ovulation Induction in Patients with PCOS as Compared to Clomiphene Citrate alone. Global Immunological & Infectious Diseases Review, VIII, 33-39.

MHRA

    MHRA : Nadeem, Iqra, Sara Malik, and Humaira Nasir. 2023. "Effect of Coenzyme Q10a and Clomiphene Citrate for Ovulation Induction in Patients with PCOS as Compared to Clomiphene Citrate alone." Global Immunological & Infectious Diseases Review, VIII: 33-39

MLA

    MLA : Nadeem, Iqra, Sara Malik, and Humaira Nasir. "Effect of Coenzyme Q10a and Clomiphene Citrate for Ovulation Induction in Patients with PCOS as Compared to Clomiphene Citrate alone." Global Immunological & Infectious Diseases Review, VIII.I (2023): 33-39 Print.

OXFORD

    OXFORD : Nadeem, Iqra, Malik, Sara, and Nasir, Humaira (2023), "Effect of Coenzyme Q10a and Clomiphene Citrate for Ovulation Induction in Patients with PCOS as Compared to Clomiphene Citrate alone", Global Immunological & Infectious Diseases Review, VIII (I), 33-39

TURABIAN

    TURABIAN : Nadeem, Iqra, Sara Malik, and Humaira Nasir. "Effect of Coenzyme Q10a and Clomiphene Citrate for Ovulation Induction in Patients with PCOS as Compared to Clomiphene Citrate alone." Global Immunological & Infectious Diseases Review VIII, no. I (2023): 33-39. https://doi.org/10.31703/giidr.2023(VIII-I).05